There are currently over 800 regional centers in the United States. It is imperative that you carefully review a center's track record and ask relevant questions before committing to a particular regional center. As an investor, your concerns are: (1) will my family and I receive permanent residence? (2) will we be able to remove conditions? and (3) will my investment be returned?
Although there are no guarantees and in fact the USCIS requires that the investment be "at risk", minimizing the risks, both immigration and financial, are in your best interest. Here is the list of USCIS Approved EB-5 Regional Centers.